Estimating heterogeneity of physical function treatment response to caloric restriction among older adults with obesity.

Estimating heterogeneity of physical function treatment response to caloric restriction among older adults with obesity.

Clinical trials conventionally test aggregate mean differences and assume homogeneous variances across treatment groups. However, significant response heterogeneity may exist. The purpose of this study was to model treatment response variability using gait speed change among older adults participati...

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Bibliographic Details
Main Authors: Daniel P Beavers, Katherine L Hsieh, Dalane W Kitzman, Stephen B Kritchevsky, Stephen P Messier, Rebecca H Neiberg, Barbara J Nicklas, W Jack Rejeski, Kristen M Beavers
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0267779&type=printable
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https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0267779&type=printable

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