Acute Hyperglycemia Due to Topical Corticosteroid Administration
We present the case of a 71-year-old man with longstanding, previously well-controlled type 1 diabetes who developed acute hyperglycemia. His insulin requirements, via his insulin pump, increased to nearly five times his typical daily dose. The patient was admitted for evaluation and treatment and s...
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| Format: | Article |
| Language: | English |
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Wiley
2019-01-01
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| Series: | Case Reports in Endocrinology |
| Online Access: | http://dx.doi.org/10.1155/2019/6058076 |
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| author | Laura Y. Sue Anna Milanesi |
| author_facet | Laura Y. Sue Anna Milanesi |
| author_sort | Laura Y. Sue |
| collection | DOAJ |
| description | We present the case of a 71-year-old man with longstanding, previously well-controlled type 1 diabetes who developed acute hyperglycemia. His insulin requirements, via his insulin pump, increased to nearly five times his typical daily dose. The patient was admitted for evaluation and treatment and started on an insulin infusion. He had minimal insulin requirements with the insulin infusion. History revealed recent use of a super potent topical corticosteroid for a psoriasis flare. The patient was transitioned back to his insulin pump, using his prior to admission settings. He was advised to discontinue using his topical corticosteroid. He had no further hyperglycemic episodes. The clinical presentation is suggestive of corticosteroid-induced hyperglycemia, suggesting that clinically significant changes can occur even with short duration use, particularly with high potency steroids used. This is to our knowledge the first case reported in which the patient required a very significant amount of extra insulin (nearly five times his typical total daily dose) after using high potency topical steroid cream. This case highlights the potentially detrimental effect of topical corticosteroid use in patients with diabetes. |
| format | Article |
| id | doaj-art-8d6972539efc46ffbf6363881ea0e501 |
| institution | Kabale University |
| issn | 2090-6501 2090-651X |
| language | English |
| publishDate | 2019-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Endocrinology |
| spelling | doaj-art-8d6972539efc46ffbf6363881ea0e5012025-02-03T01:26:00ZengWileyCase Reports in Endocrinology2090-65012090-651X2019-01-01201910.1155/2019/60580766058076Acute Hyperglycemia Due to Topical Corticosteroid AdministrationLaura Y. Sue0Anna Milanesi1VA Greater Los Angeles Healthcare System and Division of Endocrinology, Diabetes and Hypertension, Department of Medicine, UCLA David Geffen School of Medicine, 900 Veteran Avenue, 24-130 Warren Hall, Los Angeles, CA 90095, USADepartment of Medicine, Veterans Affairs Greater Los Angeles Healthcare System and Division of Endocrinology, Departments of Medicine and Physiology, UCLA David Geffen School of Medicine, 11301 Wilshire Boulevard, Los Angeles, CA 90073, USAWe present the case of a 71-year-old man with longstanding, previously well-controlled type 1 diabetes who developed acute hyperglycemia. His insulin requirements, via his insulin pump, increased to nearly five times his typical daily dose. The patient was admitted for evaluation and treatment and started on an insulin infusion. He had minimal insulin requirements with the insulin infusion. History revealed recent use of a super potent topical corticosteroid for a psoriasis flare. The patient was transitioned back to his insulin pump, using his prior to admission settings. He was advised to discontinue using his topical corticosteroid. He had no further hyperglycemic episodes. The clinical presentation is suggestive of corticosteroid-induced hyperglycemia, suggesting that clinically significant changes can occur even with short duration use, particularly with high potency steroids used. This is to our knowledge the first case reported in which the patient required a very significant amount of extra insulin (nearly five times his typical total daily dose) after using high potency topical steroid cream. This case highlights the potentially detrimental effect of topical corticosteroid use in patients with diabetes.http://dx.doi.org/10.1155/2019/6058076 |
| spellingShingle | Laura Y. Sue Anna Milanesi Acute Hyperglycemia Due to Topical Corticosteroid Administration Case Reports in Endocrinology |
| title | Acute Hyperglycemia Due to Topical Corticosteroid Administration |
| title_full | Acute Hyperglycemia Due to Topical Corticosteroid Administration |
| title_fullStr | Acute Hyperglycemia Due to Topical Corticosteroid Administration |
| title_full_unstemmed | Acute Hyperglycemia Due to Topical Corticosteroid Administration |
| title_short | Acute Hyperglycemia Due to Topical Corticosteroid Administration |
| title_sort | acute hyperglycemia due to topical corticosteroid administration |
| url | http://dx.doi.org/10.1155/2019/6058076 |
| work_keys_str_mv | AT lauraysue acutehyperglycemiaduetotopicalcorticosteroidadministration AT annamilanesi acutehyperglycemiaduetotopicalcorticosteroidadministration |