Impact of Post-Thaw Enrichment of Primary Human Hepatocytes on Steatosis, Inflammation, and Fibrosis in the TruVivo<sup>®</sup> System

Impact of Post-Thaw Enrichment of Primary Human Hepatocytes on Steatosis, Inflammation, and Fibrosis in the TruVivo<sup>®</sup> System

<b>Background</b>: Liver diseases are a global health concern. Many in vitro liver models utilize cryopreserved primary human hepatocytes (PHHs), which commonly undergo post-thaw processing through colloidal silica gradients to remove debris and enrich for a viable PHH population. Post-t...

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Bibliographic Details
Main Authors: Justin J. Odanga, Sharon M. Anderson, Sharon C. Presnell, Edward L. LeCluyse, Jingsong Chen, Jessica R. Weaver
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Pharmaceuticals
Subjects:
liver
hepatocytes
human
disease
Percoll
Online Access:https://www.mdpi.com/1424-8247/17/12/1624
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