Fifty-One Kilobase HSV-1 Plasmid Vector Can Be Packaged Using a Helper Virus-Free System and Supports Expression in the Rat Brain

Herpes simplex virus type 1 (HSV-1) plasmid vectors have a number of attractive features for gene transfer into neurons. In particular, the large size of the HSV-1 genome suggests that HSV-1 vectors might be designed to accommodate large inserts. We now report the construction and characterization o...

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Bibliographic Details
Main Authors: X. Wang, G.-r. Zhang, T. Yang, W. Zhang, A.I. Geller
Format: Article
Language:English
Published: Taylor & Francis Group 2000-01-01
Series:BioTechniques
Online Access:https://www.future-science.com/doi/10.2144/00281st05
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