Single- versus multi-fraction spine stereotactic radiosurgery (ALL-STAR) for patients with spinal metastases: a randomized phase III trial protocol

Single- versus multi-fraction spine stereotactic radiosurgery (ALL-STAR) for patients with spinal metastases: a randomized phase III trial protocol

Abstract Background For patients with spine metastases, stereotactic radiosurgery (SRS) provides excellent local control and pain response. Despite increasing use of this treatment modality, there is no consensus on the optimal dose and fractionation of spine SRS for efficacy and toxicity. We have i...

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Main Authors: Aniket Pratapneni, Daniella Klebaner, Scott Gerard Soltys, Elham Rahimy, Iris Catrice Gibbs, Steven Daniel Chang, Gordon Li, Melanie Hayden Gephart, Anand Veeravagu, Gregory Arthur Szalkowski, Xuejun Gu, Lei Wang, Cynthia Chuang, Lianli Liu, Scott Jackson, Rong Lu, Jillian Adele Skerchak, Kelly Zhe Huang, Samantha Wong, Eleanor Brown, Erqi Liu Pollom
Format: Article
Language:English
Published: BMC 2025-02-01
Series:BMC Cancer
Online Access:https://doi.org/10.1186/s12885-025-13655-6
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https://doi.org/10.1186/s12885-025-13655-6

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