Pravastatin-Induced Eczematous Eruption Mimicking Psoriasis

Background. Statins, an example of the most commonly prescribed medications to the elderly, are not without side effects. Dermatologic events are often overlooked as arising from medications, particularly those which are taken chronically. Moreover, elderly patients are prone to pharmacologic intera...

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Main Authors: Michael P. Salna, Hannah M. Singer, Ali N. Dana
Format: Article
Language:English
Published: Wiley 2017-01-01
Series:Case Reports in Dermatological Medicine
Online Access:http://dx.doi.org/10.1155/2017/3418204
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author Michael P. Salna
Hannah M. Singer
Ali N. Dana
author_facet Michael P. Salna
Hannah M. Singer
Ali N. Dana
author_sort Michael P. Salna
collection DOAJ
description Background. Statins, an example of the most commonly prescribed medications to the elderly, are not without side effects. Dermatologic events are often overlooked as arising from medications, particularly those which are taken chronically. Moreover, elderly patients are prone to pharmacologic interactions due to multiple medications. In this report, we describe a case of a statin-induced eczematous dermatitis with a psoriasis-like clinical presentation and review the skin manifestations that may arise from statin therapy. Case Presentation. An 82-year-old man with gout and hypercholesterolemia presented to dermatology clinic with new onset of pruritic, scaly erythematous plaques bilaterally on the extensor surfaces of his arms. He had never had similar lesions before. Despite various topical and systemic treatments over several months, the rash continued to evolve. The patient was then advised to discontinue his long-term statin, which led to gradual resolution of his symptoms. He was subsequently diagnosed with statin-induced eczematous dermatitis. Conclusions. This case report describes an adverse cutaneous reaction to statins that is rarely reported in the literature. Medications, including longstanding therapies, should be suspected in cases of refractory dermatologic lesions.
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spelling doaj-art-8c3bcf560bc0493fb6ffd48f96eaa6f62025-02-03T01:27:53ZengWileyCase Reports in Dermatological Medicine2090-64632090-64712017-01-01201710.1155/2017/34182043418204Pravastatin-Induced Eczematous Eruption Mimicking PsoriasisMichael P. Salna0Hannah M. Singer1Ali N. Dana2Department of Cardiothoracic Surgery, Stanford University School of Medicine, Stanford, CA, USAColumbia University College of Physicians and Surgeons, New York City, NY, USADermatology Service, James J. Peters VA Medical Center, Bronx, NY, USABackground. Statins, an example of the most commonly prescribed medications to the elderly, are not without side effects. Dermatologic events are often overlooked as arising from medications, particularly those which are taken chronically. Moreover, elderly patients are prone to pharmacologic interactions due to multiple medications. In this report, we describe a case of a statin-induced eczematous dermatitis with a psoriasis-like clinical presentation and review the skin manifestations that may arise from statin therapy. Case Presentation. An 82-year-old man with gout and hypercholesterolemia presented to dermatology clinic with new onset of pruritic, scaly erythematous plaques bilaterally on the extensor surfaces of his arms. He had never had similar lesions before. Despite various topical and systemic treatments over several months, the rash continued to evolve. The patient was then advised to discontinue his long-term statin, which led to gradual resolution of his symptoms. He was subsequently diagnosed with statin-induced eczematous dermatitis. Conclusions. This case report describes an adverse cutaneous reaction to statins that is rarely reported in the literature. Medications, including longstanding therapies, should be suspected in cases of refractory dermatologic lesions.http://dx.doi.org/10.1155/2017/3418204
spellingShingle Michael P. Salna
Hannah M. Singer
Ali N. Dana
Pravastatin-Induced Eczematous Eruption Mimicking Psoriasis
Case Reports in Dermatological Medicine
title Pravastatin-Induced Eczematous Eruption Mimicking Psoriasis
title_full Pravastatin-Induced Eczematous Eruption Mimicking Psoriasis
title_fullStr Pravastatin-Induced Eczematous Eruption Mimicking Psoriasis
title_full_unstemmed Pravastatin-Induced Eczematous Eruption Mimicking Psoriasis
title_short Pravastatin-Induced Eczematous Eruption Mimicking Psoriasis
title_sort pravastatin induced eczematous eruption mimicking psoriasis
url http://dx.doi.org/10.1155/2017/3418204
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