Depletion of key gut bacteria predicts disrupted bile acid metabolism in inflammatory bowel disease

ABSTRACT The gut microbiome plays a key role in bile acid (BA) metabolism, where a diversity of metabolic products contribute to human health and disease. In particular, Inflammatory Bowel Disease (IBD) is characterized by a low concentration of secondary bile acids (SBAs), whose transformation from...

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Bibliographic Details
Main Authors: Daniel Peterson, Christopher Weidenmaier, Sonia Timberlake, Rotem Gura Sadovsky
Format: Article
Language:English
Published: American Society for Microbiology 2025-02-01
Series:Microbiology Spectrum
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Online Access:https://journals.asm.org/doi/10.1128/spectrum.01999-24
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