PRMT5 promotes ovarian cancer growth through enhancing Warburg effect by methylating ENO1

PRMT5 promotes ovarian cancer growth through enhancing Warburg effect by methylating ENO1

Abstract Protein arginine methyltransferase 5 (PRMT5) is a major type II enzyme responsible for symmetric dimethylation of arginine (SDMA), and plays predominantly roles in human cancers, including in ovarian cancer. However, the exactly roles and underlying mechanisms of PRMT5 contributing to the p...

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Main Authors: Fei Xie, Han Zhang, Kongkai Zhu, Cheng‐Shi Jiang, Xiaoya Zhang, Hongkai Chang, Yaya Qiao, Mingming Sun, Jiyan Wang, Mukuo Wang, Junzhen Tan, Tao Wang, Lianmei Zhao, Yuan Zhang, Jianping Lin, Chunze Zhang, Shuangping Liu, Jianguo Zhao, Cheng Luo, Shuai Zhang, Changliang Shan
Format: Article
Language:English
Published: Wiley 2023-04-01
Series:MedComm
Subjects:
alpha‐enolase (ENO1)
glycolysis flux
ovarian cancer
protein arginine methyltransferase 5 (PRMT5)
symmetric dimethylation of arginine (SDMA)
Online Access:https://doi.org/10.1002/mco2.245
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https://doi.org/10.1002/mco2.245

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