Differential Regulation of DC Function, Adaptive Immunity, and MyD88 Dependence by Two Squalene Emulsion-Based Vaccine Adjuvants

Differential Regulation of DC Function, Adaptive Immunity, and MyD88 Dependence by Two Squalene Emulsion-Based Vaccine Adjuvants

MF59 and AS03 are squalene emulsion-based vaccine adjuvants with similar compositions and droplet sizes. Despite their broad use in licensed influenza vaccines, few studies compared their adjuvant effects and action mechanisms side by side. Considering the majority of adjuvants act on dendritic cell...

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Bibliographic Details
Main Authors: Jayachandra Reddy Nakkala, Yibo Li, Labone Akter, Xinliang Kang, Xinyuan Chen
Format: Article
Language:English
Published: MDPI AG 2024-05-01
Series:Vaccines
Subjects:
MF59
AS03
AddaVax
AddaS03
squalene
emulsion adjuvant
Online Access:https://www.mdpi.com/2076-393X/12/5/531
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