The impact of nutritional status on centenarians’ physical, mental, and functional health
Summary: Background & Aims: Nutrition has been described as a lifestyle factor strongly associated with health phenotypes in extreme longevity. However, little is known about its relationship with health-related outcomes in centenarians. Methods: A cross-sectional study was conducted from t...
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Elsevier
2025-04-01
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| Series: | Clinical Nutrition Open Science |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2667268525000105 |
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| author | Ivan David Lozada-Martinez Laura Vindas-Meza Sandra Castelblanco-Toro Juan Carlos Salazar-Uribe Juan-Manuel Anaya |
| author_facet | Ivan David Lozada-Martinez Laura Vindas-Meza Sandra Castelblanco-Toro Juan Carlos Salazar-Uribe Juan-Manuel Anaya |
| author_sort | Ivan David Lozada-Martinez |
| collection | DOAJ |
| description | Summary: Background & Aims: Nutrition has been described as a lifestyle factor strongly associated with health phenotypes in extreme longevity. However, little is known about its relationship with health-related outcomes in centenarians. Methods: A cross-sectional study was conducted from the COOLCEN cohort. The Mini Nutritional Assessment (MNA) and the Prognostic Nutritional Index (PNI) were used to determine nutritional status, which were correlated with clinical, health status, and biochemical variables. Results: The sample included 139 centenarians, 74% (n=103) were female. Centenarians at risk of malnutrition (47%; n=66) and those with an absolute PNI value < 38.8 (54%) represented the most significant proportion. MNA was positively correlated with functional independence (r2 = 0.734, P < 0.05), cognitive assessment (r2 = 0.650, P < 0.05), and functional performance (r2 = 0.619, P < 0.05). Inadequate physical performance, frailty, sarcopenia, severe dementia, some degree of dependency, low PNI, and avoiding the use of dental prosthesis were significantly associated with nutritional vulnerability (P < 0.05). Conclusions: This study identified that nutritional status in centenarians is associated with functional and cognitive status, physical performance, use of dental prostheses, and specific biochemical and anthropometric variables. These findings are relevant for decision-making in general and specialized healthcare and for public health policymakers to build evidence-based strategies to promote healthy aging. |
| format | Article |
| id | doaj-art-8bb17ee9a6de4f358ada9b1670880df5 |
| institution | Kabale University |
| issn | 2667-2685 |
| language | English |
| publishDate | 2025-04-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Clinical Nutrition Open Science |
| spelling | doaj-art-8bb17ee9a6de4f358ada9b1670880df52025-02-03T04:17:07ZengElsevierClinical Nutrition Open Science2667-26852025-04-01601020The impact of nutritional status on centenarians’ physical, mental, and functional healthIvan David Lozada-Martinez0Laura Vindas-Meza1Sandra Castelblanco-Toro2Juan Carlos Salazar-Uribe3Juan-Manuel Anaya4Universidad de la Costa, Barranquilla, Colombia; Centenarians Alliance, Bogota, Colombia; Corresponding author. Universidad de la Costa, Barranquilla, Colombia.Asociación Península de Nicoya Zona Azul, Nicoya, Costa RicaCentenarians Alliance, Bogota, Colombia; Intellectus Memory and Cognition Center, Hospital Universitario San Ignacio, Institute of Aging, Faculty of Medicine, Pontificia Universidad Javeriana, Bogotá, ColombiaCentenarians Alliance, Bogota, Colombia; Universidad Nacional de Colombia, Medellín, ColombiaUniversidad de la Costa, Barranquilla, Colombia; Centenarians Alliance, Bogota, Colombia; Corresponding author. Universidad de la Costa, Barranquilla, Colombia.Summary: Background & Aims: Nutrition has been described as a lifestyle factor strongly associated with health phenotypes in extreme longevity. However, little is known about its relationship with health-related outcomes in centenarians. Methods: A cross-sectional study was conducted from the COOLCEN cohort. The Mini Nutritional Assessment (MNA) and the Prognostic Nutritional Index (PNI) were used to determine nutritional status, which were correlated with clinical, health status, and biochemical variables. Results: The sample included 139 centenarians, 74% (n=103) were female. Centenarians at risk of malnutrition (47%; n=66) and those with an absolute PNI value < 38.8 (54%) represented the most significant proportion. MNA was positively correlated with functional independence (r2 = 0.734, P < 0.05), cognitive assessment (r2 = 0.650, P < 0.05), and functional performance (r2 = 0.619, P < 0.05). Inadequate physical performance, frailty, sarcopenia, severe dementia, some degree of dependency, low PNI, and avoiding the use of dental prosthesis were significantly associated with nutritional vulnerability (P < 0.05). Conclusions: This study identified that nutritional status in centenarians is associated with functional and cognitive status, physical performance, use of dental prostheses, and specific biochemical and anthropometric variables. These findings are relevant for decision-making in general and specialized healthcare and for public health policymakers to build evidence-based strategies to promote healthy aging.http://www.sciencedirect.com/science/article/pii/S2667268525000105CentenariansLongevityNutritional statusPatient outcome assessmentHealth status |
| spellingShingle | Ivan David Lozada-Martinez Laura Vindas-Meza Sandra Castelblanco-Toro Juan Carlos Salazar-Uribe Juan-Manuel Anaya The impact of nutritional status on centenarians’ physical, mental, and functional health Clinical Nutrition Open Science Centenarians Longevity Nutritional status Patient outcome assessment Health status |
| title | The impact of nutritional status on centenarians’ physical, mental, and functional health |
| title_full | The impact of nutritional status on centenarians’ physical, mental, and functional health |
| title_fullStr | The impact of nutritional status on centenarians’ physical, mental, and functional health |
| title_full_unstemmed | The impact of nutritional status on centenarians’ physical, mental, and functional health |
| title_short | The impact of nutritional status on centenarians’ physical, mental, and functional health |
| title_sort | impact of nutritional status on centenarians physical mental and functional health |
| topic | Centenarians Longevity Nutritional status Patient outcome assessment Health status |
| url | http://www.sciencedirect.com/science/article/pii/S2667268525000105 |
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