Computational analysis of missense mutations in squalene epoxidase associated with terbinafine resistance in clinically reported dermatophytes
Abstract Dermatophyte infections, as a significant public health threats, are increasingly associated with antifungal drug resistance, particularly to terbinafine. Mutations in the squalene epoxidase (SQLE) gene have been linked to resistance by altering amino acid residues and interfering with drug...
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| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-05-01
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| Series: | Scientific Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.1038/s41598-025-03300-4 |
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