Frequency and Molecular Characteristics of Mismatch Repair-deficient Status among Multiple Synchronous Colorectal Cancers

Frequency and Molecular Characteristics of Mismatch Repair-deficient Status among Multiple Synchronous Colorectal Cancers

Objectives: Mismatch repair (MMR)-deficient (dMMR) colorectal cancer (CRC) have been largely categorized into three subtypes: MLH1-methylated, Lynch syndrome (LS)-associated, and Lynch-like syndrome (LLS)-associated. No studies have examined the prevalence and subtypes of synchronously diagnosed dMM...

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Main Authors: Kenichi Chikatani, Noriyasu Chika, Noriko Tanabe, Yoshiko Mori, Okihide Suzuki, Takatoshi Matsuyama, Keiichiro Ishibashi, Hidetaka Eguchi, Yasushi Okazaki, Tatsuro Yamaguchi, Hideyuki Ishida
Format: Article
Language:English
Published: The Japan Society of Coloproctology 2025-01-01
Series:Journal of the Anus, Rectum and Colon
Subjects:
lynch syndrome
lynch-like syndrome
mismatch repair-deficient
colorectal cancer
synchronous colorectal cancer
Online Access:https://www.jstage.jst.go.jp/article/jarc/9/1/9_2024-092/_pdf/-char/en
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https://www.jstage.jst.go.jp/article/jarc/9/1/9_2024-092/_pdf/-char/en

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