A Review of Antibiotic Efficacy in COVID-19 Control
Severe acute respiratory disease is associated with chronic secondary infections that exacerbate symptoms and mortality. So far, many drugs have been introduced to treat this disease, none of which effectively control the coronavirus. Numerous studies have shown that mitochondria, as the center of c...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2023-01-01
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| Series: | Journal of Immunology Research |
| Online Access: | http://dx.doi.org/10.1155/2023/6687437 |
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| _version_ | 1832546609825579008 |
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| author | Hamidreza Hekmat Aziz Rasooli Zeinab Siami Kauthar Amir Rutajengwa Zahra Vahabi Fatemeh Alsadat Mirzadeh |
| author_facet | Hamidreza Hekmat Aziz Rasooli Zeinab Siami Kauthar Amir Rutajengwa Zahra Vahabi Fatemeh Alsadat Mirzadeh |
| author_sort | Hamidreza Hekmat |
| collection | DOAJ |
| description | Severe acute respiratory disease is associated with chronic secondary infections that exacerbate symptoms and mortality. So far, many drugs have been introduced to treat this disease, none of which effectively control the coronavirus. Numerous studies have shown that mitochondria, as the center of cell biogenesis, are vulnerable to drugs, especially antibiotics. Antibiotics were widely prescribed during the early phase of the pandemic. We performed a literature review to assess the reasons, evidence, and practices on the use of antibiotics in coronavirus disease 2019 (COVID-19) in- and outpatients. The current research found widespread usage of antibiotics, mostly in an empirical context, among COVID-19 hospitalized patients. The effectiveness of this approach has not been established. Given the high death rate linked with secondary infections in COVID-19 patients and the developing antimicrobial resistance, further study is urgently needed to identify the most appropriate rationale for antibiotic therapy in these patients. |
| format | Article |
| id | doaj-art-8b31fcb2f6cd4b3f99f3937bd2835008 |
| institution | Kabale University |
| issn | 2314-7156 |
| language | English |
| publishDate | 2023-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Immunology Research |
| spelling | doaj-art-8b31fcb2f6cd4b3f99f3937bd28350082025-02-03T06:47:41ZengWileyJournal of Immunology Research2314-71562023-01-01202310.1155/2023/6687437A Review of Antibiotic Efficacy in COVID-19 ControlHamidreza Hekmat0Aziz Rasooli1Zeinab Siami2Kauthar Amir Rutajengwa3Zahra Vahabi4Fatemeh Alsadat Mirzadeh5Cardiology DepartmentDepartment of Emergency MedicineDepartment of Infectious Disease, Ziaeian HospitalMedical School DepartmentGeriatric DepartmentGeriatric DepartmentSevere acute respiratory disease is associated with chronic secondary infections that exacerbate symptoms and mortality. So far, many drugs have been introduced to treat this disease, none of which effectively control the coronavirus. Numerous studies have shown that mitochondria, as the center of cell biogenesis, are vulnerable to drugs, especially antibiotics. Antibiotics were widely prescribed during the early phase of the pandemic. We performed a literature review to assess the reasons, evidence, and practices on the use of antibiotics in coronavirus disease 2019 (COVID-19) in- and outpatients. The current research found widespread usage of antibiotics, mostly in an empirical context, among COVID-19 hospitalized patients. The effectiveness of this approach has not been established. Given the high death rate linked with secondary infections in COVID-19 patients and the developing antimicrobial resistance, further study is urgently needed to identify the most appropriate rationale for antibiotic therapy in these patients.http://dx.doi.org/10.1155/2023/6687437 |
| spellingShingle | Hamidreza Hekmat Aziz Rasooli Zeinab Siami Kauthar Amir Rutajengwa Zahra Vahabi Fatemeh Alsadat Mirzadeh A Review of Antibiotic Efficacy in COVID-19 Control Journal of Immunology Research |
| title | A Review of Antibiotic Efficacy in COVID-19 Control |
| title_full | A Review of Antibiotic Efficacy in COVID-19 Control |
| title_fullStr | A Review of Antibiotic Efficacy in COVID-19 Control |
| title_full_unstemmed | A Review of Antibiotic Efficacy in COVID-19 Control |
| title_short | A Review of Antibiotic Efficacy in COVID-19 Control |
| title_sort | review of antibiotic efficacy in covid 19 control |
| url | http://dx.doi.org/10.1155/2023/6687437 |
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