The Neuroactivation of Cognitive Processes Investigated with SPECT

The last ten years have seen the development and expansion of an exciting new field of neuroscientific research; functional mapping of the human brain. Whilst many of the questions addressed by this area of research could be answered using SPECT, relatively few SPECT activation studies of this kind...

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Main Authors: Daniela Montaldi, Andrew R. Mayes
Format: Article
Language:English
Published: Wiley 2000-01-01
Series:Behavioural Neurology
Online Access:http://dx.doi.org/10.1155/2000/525163
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author Daniela Montaldi
Andrew R. Mayes
author_facet Daniela Montaldi
Andrew R. Mayes
author_sort Daniela Montaldi
collection DOAJ
description The last ten years have seen the development and expansion of an exciting new field of neuroscientific research; functional mapping of the human brain. Whilst many of the questions addressed by this area of research could be answered using SPECT, relatively few SPECT activation studies of this kind have been carried out. The present paper combines an evaluation of SPECT procedures used for neuroactivation studies, and their comparison with other imaging modalities (i.e., PET and fMRI), with a review of SPECT neuroactivation studies that yield information concerning normal brain function with a particular emphasis on the brain activations produced by memory processing. The paper aims to describe and counter common misunderstandings regarding potential limitations of the SPECT technique, to explain and illustrate which SPECT procedures best fulfill the requirements of a neuroactivation study, and how best to obtain information about normal brain function (whether using normal healthy subjects or patients) and finally to highlight SPECT’s potential future role in the functional mapping of the human brain.
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spelling doaj-art-8b29d7b1e93740e686a9cbbc6edda6da2025-02-03T01:06:17ZengWileyBehavioural Neurology0953-41801875-85842000-01-01121-2536710.1155/2000/525163The Neuroactivation of Cognitive Processes Investigated with SPECTDaniela Montaldi0Andrew R. Mayes1Department of Psychology, University of Liverpool, UKDepartment of Psychology, University of Liverpool, UKThe last ten years have seen the development and expansion of an exciting new field of neuroscientific research; functional mapping of the human brain. Whilst many of the questions addressed by this area of research could be answered using SPECT, relatively few SPECT activation studies of this kind have been carried out. The present paper combines an evaluation of SPECT procedures used for neuroactivation studies, and their comparison with other imaging modalities (i.e., PET and fMRI), with a review of SPECT neuroactivation studies that yield information concerning normal brain function with a particular emphasis on the brain activations produced by memory processing. The paper aims to describe and counter common misunderstandings regarding potential limitations of the SPECT technique, to explain and illustrate which SPECT procedures best fulfill the requirements of a neuroactivation study, and how best to obtain information about normal brain function (whether using normal healthy subjects or patients) and finally to highlight SPECT’s potential future role in the functional mapping of the human brain.http://dx.doi.org/10.1155/2000/525163
spellingShingle Daniela Montaldi
Andrew R. Mayes
The Neuroactivation of Cognitive Processes Investigated with SPECT
Behavioural Neurology
title The Neuroactivation of Cognitive Processes Investigated with SPECT
title_full The Neuroactivation of Cognitive Processes Investigated with SPECT
title_fullStr The Neuroactivation of Cognitive Processes Investigated with SPECT
title_full_unstemmed The Neuroactivation of Cognitive Processes Investigated with SPECT
title_short The Neuroactivation of Cognitive Processes Investigated with SPECT
title_sort neuroactivation of cognitive processes investigated with spect
url http://dx.doi.org/10.1155/2000/525163
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