Sex-based differences in the long-term fate of hippocampal neurons born after a traumatic brain injury

Sex-based differences in the long-term fate of hippocampal neurons born after a traumatic brain injury

IntroductionModerate-to-severe traumatic brain injury (TBI) results in an early loss of immature hippocampal granule cells and the activation of typically quiescent neural stem cells (NSCs) in the dentate gyrus. Activation of NSCs leads to a robust increase in proliferation and generation of neural...

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Bibliographic Details
Main Authors: Hannah C. Downing, Ashley B. Glover, Jessica E. Gebhardt, Katherine L. Thompson, Kathryn E. Saatman
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-02-01
Series:Frontiers in Behavioral Neuroscience
Subjects:
dendrite morphology
dentate gyrus
hippocampus
mossy fiber boutons
neurogenesis
sex differences
Online Access:https://www.frontiersin.org/articles/10.3389/fnbeh.2025.1523969/full
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