Predicting cell morphological responses to perturbations using generative modeling

Abstract Advancements in high-throughput screenings enable the exploration of rich phenotypic readouts through high-content microscopy, expediting the development of phenotype-based drug discovery. However, analyzing large and complex high-content imaging screenings remains challenging due to incomp...

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Bibliographic Details
Main Authors: Alessandro Palma, Fabian J. Theis, Mohammad Lotfollahi
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-55707-8
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