High risk oral contraceptive hormones do not directly enhance endothelial cell procoagulant activity in vitro.

High risk oral contraceptive hormones do not directly enhance endothelial cell procoagulant activity in vitro.

<h4>Background</h4>Oral contraceptive (OC) use increases venous thromboembolism risk 2-5-fold. Procoagulant changes can be detected in plasma from OC users even without thrombosis, but cellular mechanisms that provoke thrombosis have not been identified. Endothelial cell (EC) dysfunction...

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Main Authors: Emma G Bouck, Marios Arvanitis, William O Osburn, Yaqiu Sang, Paula Reventun, Homa K Ahmadzia, Nicholas L Smith, Charles J Lowenstein, Alisa S Wolberg
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0284333&type=printable
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