Paramedic Recognition of Sepsis in the Prehospital Setting: A Prospective Observational Study

Background. Patients with sepsis benefit from early diagnosis and treatment. Accurate paramedic recognition of sepsis is important to initiate care promptly for patients who arrive by Emergency Medical Services. Methods. Prospective observational study of adult patients (age ≥ 16 years) transported...

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Main Authors: Robert S. Green, Andrew H. Travers, Edward Cain, Samuel G. Campbell, Jan L. Jensen, David A. Petrie, Mete Erdogan, Gredi Patrick, Ward Patrick
Format: Article
Language:English
Published: Wiley 2016-01-01
Series:Emergency Medicine International
Online Access:http://dx.doi.org/10.1155/2016/6717261
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author Robert S. Green
Andrew H. Travers
Edward Cain
Samuel G. Campbell
Jan L. Jensen
David A. Petrie
Mete Erdogan
Gredi Patrick
Ward Patrick
author_facet Robert S. Green
Andrew H. Travers
Edward Cain
Samuel G. Campbell
Jan L. Jensen
David A. Petrie
Mete Erdogan
Gredi Patrick
Ward Patrick
author_sort Robert S. Green
collection DOAJ
description Background. Patients with sepsis benefit from early diagnosis and treatment. Accurate paramedic recognition of sepsis is important to initiate care promptly for patients who arrive by Emergency Medical Services. Methods. Prospective observational study of adult patients (age ≥ 16 years) transported by paramedics to the emergency department (ED) of a Canadian tertiary hospital. Paramedic identification of sepsis was assessed using a novel prehospital sepsis screening tool developed by the study team and compared to blind, independent documentation of ED diagnoses by attending emergency physicians (EPs). Specificity, sensitivity, accuracy, positive and negative predictive value, and likelihood ratios were calculated with 95% confidence intervals. Results. Overall, 629 patients were included in the analysis. Sepsis was identified by paramedics in 170 (27.0%) patients and by EPs in 71 (11.3%) patients. Sensitivity of paramedic sepsis identification compared to EP diagnosis was 73.2% (95% CI 61.4–83.0), while specificity was 78.8% (95% CI 75.2–82.2). The accuracy of paramedic identification of sepsis was 78.2% (492/629, 52 true positive, 440 true negative). Positive and negative predictive values were 30.6% (95% CI 23.8–38.1) and 95.9% (95% CI 93.6–97.5), respectively. Conclusion. Using a novel prehospital sepsis screening tool, paramedic recognition of sepsis had greater specificity than sensitivity with reasonable accuracy.
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spelling doaj-art-89f95e5084044eef8f585f3a5f322f132025-02-03T05:54:19ZengWileyEmergency Medicine International2090-28402090-28592016-01-01201610.1155/2016/67172616717261Paramedic Recognition of Sepsis in the Prehospital Setting: A Prospective Observational StudyRobert S. Green0Andrew H. Travers1Edward Cain2Samuel G. Campbell3Jan L. Jensen4David A. Petrie5Mete Erdogan6Gredi Patrick7Ward Patrick8Department of Critical Care, Dalhousie University, Suite 377, Bethune Building, 1276 South Park Street, Halifax, NS, B3H 2Y9, CanadaDepartment of Emergency Medicine, Dalhousie University, Division of EMS, 1796 Summer Street, Halifax Infirmary, Suite 355, Halifax, NS, B3H 3A7, CanadaDepartment of Emergency Medicine, Dalhousie University, Division of EMS, 1796 Summer Street, Halifax Infirmary, Suite 355, Halifax, NS, B3H 3A7, CanadaDepartment of Emergency Medicine, Dalhousie University, Division of EMS, 1796 Summer Street, Halifax Infirmary, Suite 355, Halifax, NS, B3H 3A7, CanadaDepartment of Emergency Medicine, Dalhousie University, Division of EMS, 1796 Summer Street, Halifax Infirmary, Suite 355, Halifax, NS, B3H 3A7, CanadaDepartment of Emergency Medicine, Dalhousie University, Division of EMS, 1796 Summer Street, Halifax Infirmary, Suite 355, Halifax, NS, B3H 3A7, CanadaTrauma Nova Scotia, Room 1-026B, Centennial Building, 1276 South Park Street, Halifax, NS, B3H 2Y9, CanadaPerformance Excellence, Nova Scotia Health Authority, Halifax, NS, B3H 4R2, CanadaDepartment of Critical Care, Dalhousie University, Suite 377, Bethune Building, 1276 South Park Street, Halifax, NS, B3H 2Y9, CanadaBackground. Patients with sepsis benefit from early diagnosis and treatment. Accurate paramedic recognition of sepsis is important to initiate care promptly for patients who arrive by Emergency Medical Services. Methods. Prospective observational study of adult patients (age ≥ 16 years) transported by paramedics to the emergency department (ED) of a Canadian tertiary hospital. Paramedic identification of sepsis was assessed using a novel prehospital sepsis screening tool developed by the study team and compared to blind, independent documentation of ED diagnoses by attending emergency physicians (EPs). Specificity, sensitivity, accuracy, positive and negative predictive value, and likelihood ratios were calculated with 95% confidence intervals. Results. Overall, 629 patients were included in the analysis. Sepsis was identified by paramedics in 170 (27.0%) patients and by EPs in 71 (11.3%) patients. Sensitivity of paramedic sepsis identification compared to EP diagnosis was 73.2% (95% CI 61.4–83.0), while specificity was 78.8% (95% CI 75.2–82.2). The accuracy of paramedic identification of sepsis was 78.2% (492/629, 52 true positive, 440 true negative). Positive and negative predictive values were 30.6% (95% CI 23.8–38.1) and 95.9% (95% CI 93.6–97.5), respectively. Conclusion. Using a novel prehospital sepsis screening tool, paramedic recognition of sepsis had greater specificity than sensitivity with reasonable accuracy.http://dx.doi.org/10.1155/2016/6717261
spellingShingle Robert S. Green
Andrew H. Travers
Edward Cain
Samuel G. Campbell
Jan L. Jensen
David A. Petrie
Mete Erdogan
Gredi Patrick
Ward Patrick
Paramedic Recognition of Sepsis in the Prehospital Setting: A Prospective Observational Study
Emergency Medicine International
title Paramedic Recognition of Sepsis in the Prehospital Setting: A Prospective Observational Study
title_full Paramedic Recognition of Sepsis in the Prehospital Setting: A Prospective Observational Study
title_fullStr Paramedic Recognition of Sepsis in the Prehospital Setting: A Prospective Observational Study
title_full_unstemmed Paramedic Recognition of Sepsis in the Prehospital Setting: A Prospective Observational Study
title_short Paramedic Recognition of Sepsis in the Prehospital Setting: A Prospective Observational Study
title_sort paramedic recognition of sepsis in the prehospital setting a prospective observational study
url http://dx.doi.org/10.1155/2016/6717261
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