Formulation and Bioequivalence Evaluation of a Miniaturized Fexofenadine Hydrochloride Tablet

Formulation and Bioequivalence Evaluation of a Miniaturized Fexofenadine Hydrochloride Tablet

<b>Background:</b> Fexofenadine hydrochloride (FEX) is widely used to treat allergic rhinitis. However, poor solubility, high cohesiveness, and risk of polymorphic transformation present significant formulation challenges. Conventional FEX tablet formulations are large and may pose swall...

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Main Authors: Woo-Yul Song, Chang-Soo Han, Won-Sang Yu, Jae-Won Jang, Gyoung-Won Kim, Yoo-Shin Jeon, Young-Jin Kim, So-Jeong Jeong, Ji-Hyun Kang, Dong-Wook Kim, Yun-Sang Park, Chun-Woong Park
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Pharmaceutics
Subjects:
miniaturized
organic solvent
porous carrier
scale-up
bioequivalence
Online Access:https://www.mdpi.com/1999-4923/17/6/756
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