Randomized clinical studies assessing the pharmacokinetics and subjective effects of vuse alto electronic nicotine delivery systems

Randomized clinical studies assessing the pharmacokinetics and subjective effects of vuse alto electronic nicotine delivery systems

Abstract The US FDA recommends assessment of abuse liability (AL) for premarket tobacco product applications (PMTAs) to determine whether a new tobacco product is appropriate for the protection of public health (APPH). To assess the AL and nicotine uptake of Vuse Alto electronic nicotine tobacco pro...

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Bibliographic Details
Main Authors: Kristen Prevette, Kristen G. Jordan, Brian M. Keyser, Milly N. Kanobe, Tao Jin, Sarah Ayoku, John Darnell, Patrudu Makena, Sarah A. Baxter
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
Abuse liability
E-cigarettes
Nicotine pharmacokinetics
Subjective measures
Vuse Alto
Products
Online Access:https://doi.org/10.1038/s41598-025-06716-0
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https://doi.org/10.1038/s41598-025-06716-0

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