Degradation rather than disassembly of necrotic debris is essential to enhance recovery after acute liver injury

Degradation rather than disassembly of necrotic debris is essential to enhance recovery after acute liver injury

Abstract Necrotic cell death causes loss of membrane integrity, release of intracellular contents and deposition of necrotic cell debris. Effective clearance of this debris is crucial for resolving inflammation and promoting tissue recovery. While leukocyte phagocytosis plays a major role, soluble f...

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Bibliographic Details
Main Authors: Sara Schuermans, Jusal Quanico, Caine Kestens, Sofie Vandendriessche, Emily Slowikowski, Maria-Laura Crijns, Noëmie Pörtner, Nele Berghmans, Geert Baggerman, Matheus Silvério Mattos, Paul Proost, Pedro Elias Marques
Format: Article
Language:English
Published: Springer 2025-04-01
Series:Cellular and Molecular Life Sciences
Subjects:
Cell death
Necrotic cell debris
DNase
Peptide
Fibrinolysis
Online Access:https://doi.org/10.1007/s00018-025-05720-x
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https://doi.org/10.1007/s00018-025-05720-x

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