Pharmacokinetics of tebipenem pivoxil used in children suffering from shigellosis: a pilot study in Bangladesh

Pharmacokinetics of tebipenem pivoxil used in children suffering from shigellosis: a pilot study in Bangladesh

Abstract With increasing antibiotic resistance in gram-negative bacteria, including those causing Shigellosis, evidence of safety and pharmacokinetics data on new oral antibiotics is crucial. We aimed to investigate the safety and pharmacokinetic properties of an oral carbapenem, tebipenem pivoxil,...

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Main Authors: Sharika Nuzhat, Md Ridwan Islam, Syed Jayedul Bashar, Subhasish Das, Rukaeya Amin, Firdausi Qadri, Farhana Khanam, Dilruba Ahmed, Patricia B. Pavlinac, Cindy X. Zhang, Samuel L. M. Arnold, Amy Newlands, Mohammod Jobayer Chisti, Tahmeed Ahmed
Format: Article
Language:English
Published: Nature Portfolio 2024-12-01
Series:Scientific Reports
Subjects:
Tebipenem
Pharmacokinetics
Dysentery
Shigellosis
Under-5 children
Online Access:https://doi.org/10.1038/s41598-024-83549-3
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https://doi.org/10.1038/s41598-024-83549-3

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