Potential role of P4HB in the tumor microenvironment and its clinical prognostic value: a comprehensive pan-cancer analysis and experimental validation with a focus on KIRC

Potential role of P4HB in the tumor microenvironment and its clinical prognostic value: a comprehensive pan-cancer analysis and experimental validation with a focus on KIRC

Abstract Background Tumor microenvironment (TME) plays a crucial role in tumor growth and metastasis. Exploring biomarkers that are significantly associated with TME can help guide individualized treatment of patients. Methods We analyzed the expression and survival of P4HB in pan-cancer through the...

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Bibliographic Details
Main Authors: Linxue Zhang, Yu-wei Li, Tianyi Xie, Ke Sun, Xiang Huang, Wei Xiong, Rui-ji Liu
Format: Article
Language:English
Published: BMC 2025-01-01
Series:Cancer Cell International
Subjects:
P4HB
Pan-cancer
Tumor microenvironment
Kidney renal clear cell carcinoma
Immune checkpoint molecules
Online Access:https://doi.org/10.1186/s12935-024-03575-z
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https://doi.org/10.1186/s12935-024-03575-z

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