Sex and APOE genotype modulate neuropsychological profile and depression in temporal lobe epilepsy

Sex and APOE genotype modulate neuropsychological profile and depression in temporal lobe epilepsy

IntroductionTemporal lobe epilepsy is the most common form of focal epilepsy, often associated with cognitive impairments, particularly in memory functions, and depression. Sex and APOE ε4 genotype play a crucial role in modulating cognitive outcomes and depression in various neurological conditions...

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Main Authors: Francesco Bruno, Patrizia Spadafora, Ida Veltri, Mario L. Cuconati, Francesca Condino, Annamaria Cerantonio, Selene De Benedittis, Beatrice M. Greco, Gemma Di Palma, Olivier Gallo, Luigi Citrigno, Antonio Qualtieri, Maurizio Cundari, Francesca Cavalcanti
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Neuroscience
Subjects:
temporal lobe epilepsy
APOE
sex
depression
neuropsychology
memory
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2024.1514902/full
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https://www.frontiersin.org/articles/10.3389/fnins.2024.1514902/full

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