Traditional Chinese Medicine Protects against Cytokine Production as the Potential Immunosuppressive Agents in Atherosclerosis
Atherosclerosis is a chronic inflammatory disease caused by dyslipidemia and mediated by both innate and adaptive immune responses. Inflammation is a critical factor at all stages of atherosclerosis progression. Proinflammatory cytokines accelerate atherosclerosis progression, while anti-inflammator...
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| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2017-01-01
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| Series: | Journal of Immunology Research |
| Online Access: | http://dx.doi.org/10.1155/2017/7424307 |
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| _version_ | 1832563368787968000 |
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| author | Yan Ren Wei Qiao Dongliang Fu Zhiwei Han Wei Liu Weijie Ye Zunjing Liu |
| author_facet | Yan Ren Wei Qiao Dongliang Fu Zhiwei Han Wei Liu Weijie Ye Zunjing Liu |
| author_sort | Yan Ren |
| collection | DOAJ |
| description | Atherosclerosis is a chronic inflammatory disease caused by dyslipidemia and mediated by both innate and adaptive immune responses. Inflammation is a critical factor at all stages of atherosclerosis progression. Proinflammatory cytokines accelerate atherosclerosis progression, while anti-inflammatory cytokines ameliorate the disease. Accordingly, strategies to inhibit immune activation and impede immune responses towards anti-inflammatory activity are an alternative therapeutic strategy to conventional chemotherapy on cardiocerebrovascular outcomes. Since a number of Chinese medicinal plants have been used traditionally to prevent and treat atherosclerosis, it is reasonable to assume that the plants used for such disease may suppress the immune responses and the resultant inflammation. This review focuses on plants that have immunomodulatory effects on the production of inflammatory cytokine burst and are used in Chinese traditional medicine for the prevention and therapy of atherosclerosis. |
| format | Article |
| id | doaj-art-893154deb7a74c0c955a9623a656daf3 |
| institution | Kabale University |
| issn | 2314-8861 2314-7156 |
| language | English |
| publishDate | 2017-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Immunology Research |
| spelling | doaj-art-893154deb7a74c0c955a9623a656daf32025-02-03T01:20:23ZengWileyJournal of Immunology Research2314-88612314-71562017-01-01201710.1155/2017/74243077424307Traditional Chinese Medicine Protects against Cytokine Production as the Potential Immunosuppressive Agents in AtherosclerosisYan Ren0Wei Qiao1Dongliang Fu2Zhiwei Han3Wei Liu4Weijie Ye5Zunjing Liu6Department of Cardiology, China-Japan Friendship Hospital, Beijing 100029, ChinaDepartment of Cardiology, China-Japan Friendship Hospital, Beijing 100029, ChinaDepartment of Cardiology, China-Japan Friendship Hospital, Beijing 100029, ChinaDepartment of Cardiology, China-Japan Friendship Hospital, Beijing 100029, ChinaDepartment of Neurology, China-Japan Friendship Hospital, Beijing 100029, ChinaDepartment of Neurology, China-Japan Friendship Hospital, Beijing 100029, ChinaDepartment of Neurology, China-Japan Friendship Hospital, Beijing 100029, ChinaAtherosclerosis is a chronic inflammatory disease caused by dyslipidemia and mediated by both innate and adaptive immune responses. Inflammation is a critical factor at all stages of atherosclerosis progression. Proinflammatory cytokines accelerate atherosclerosis progression, while anti-inflammatory cytokines ameliorate the disease. Accordingly, strategies to inhibit immune activation and impede immune responses towards anti-inflammatory activity are an alternative therapeutic strategy to conventional chemotherapy on cardiocerebrovascular outcomes. Since a number of Chinese medicinal plants have been used traditionally to prevent and treat atherosclerosis, it is reasonable to assume that the plants used for such disease may suppress the immune responses and the resultant inflammation. This review focuses on plants that have immunomodulatory effects on the production of inflammatory cytokine burst and are used in Chinese traditional medicine for the prevention and therapy of atherosclerosis.http://dx.doi.org/10.1155/2017/7424307 |
| spellingShingle | Yan Ren Wei Qiao Dongliang Fu Zhiwei Han Wei Liu Weijie Ye Zunjing Liu Traditional Chinese Medicine Protects against Cytokine Production as the Potential Immunosuppressive Agents in Atherosclerosis Journal of Immunology Research |
| title | Traditional Chinese Medicine Protects against Cytokine Production as the Potential Immunosuppressive Agents in Atherosclerosis |
| title_full | Traditional Chinese Medicine Protects against Cytokine Production as the Potential Immunosuppressive Agents in Atherosclerosis |
| title_fullStr | Traditional Chinese Medicine Protects against Cytokine Production as the Potential Immunosuppressive Agents in Atherosclerosis |
| title_full_unstemmed | Traditional Chinese Medicine Protects against Cytokine Production as the Potential Immunosuppressive Agents in Atherosclerosis |
| title_short | Traditional Chinese Medicine Protects against Cytokine Production as the Potential Immunosuppressive Agents in Atherosclerosis |
| title_sort | traditional chinese medicine protects against cytokine production as the potential immunosuppressive agents in atherosclerosis |
| url | http://dx.doi.org/10.1155/2017/7424307 |
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