Characterization of a thermostable uricase derived from Thermoactinospora rubra YIM 77501T and its heat-resistant mechanism

Characterization of a thermostable uricase derived from Thermoactinospora rubra YIM 77501T and its heat-resistant mechanism

IntroductionUricases are oxidative enzymes that catalyze the conversion of uric acid to allantoin and hydrogen peroxide, widely utilized in uric acid testing and the treatment of gout, hyperuricemia, and Tumor Lysis Syndrome (TLS). The search for uricases with long-term thermostability has become a...

Full description

Saved in:
Bibliographic Details
Main Authors: Xin Yan, Lan-Xin Tang, Maite Ortúzar, Li-Quan Yang, Peng Sang, Na-Ying Jin, Lin-Hua Li, Zheng-Feng Yang, Yan-Wen Wang, Wen-Jun Li, Wei Hu, Yi-Rui Yin
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Microbiology
Subjects:
uricase
Thermoactinospora rubra YIM 77501T
thermostable
heat-resistant mechanism
degrade uric acid
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2025.1615845/full
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://www.frontiersin.org/articles/10.3389/fmicb.2025.1615845/full

Similar Items