DDX50 cooperates with STAU1 to effect stabilization of pro-differentiation RNAs

DDX50 cooperates with STAU1 to effect stabilization of pro-differentiation RNAs

Summary: Glucose binding can alter protein oligomerization to enable differentiation. Here, we demonstrate that glucose binding is a general capacity of DExD/H-box RNA helicases, including DDX50, which was found to be essential for the differentiation of diverse cell types. Glucose binding to conser...

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Main Authors: Weili Miao, Douglas F. Porter, Zurab Siprashvili, Ian D. Ferguson, Luca Ducoli, Duy T. Nguyen, Lisa A. Ko, Vanessa Lopez-Pajares, Suhas Srinivasan, Audrey W. Hong, Yen-Yu Yang, Zhongwen Cao, Robin M. Meyers, Jordan M. Meyers, Shiying Tao, Yinsheng Wang, Paul A. Khavari
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Cell Reports
Subjects:
CP: Molecular biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124724015250
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