Phospho-relay feedback loops control egress vs. intracellular development in Toxoplasma gondii

Summary: The intracellular parasite Toxoplasma gondii alternates between a motile invasive and a quiescent intracellular replicative form, yet how these transitions are regulated is unknown. A positive feedback loop involving protein kinase G (PKG) and calcium-dependent PKs (CDPKs) controls motility...

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Bibliographic Details
Main Authors: Ja E. Claywell, Yong Fu, L. David Sibley
Format: Article
Language:English
Published: Elsevier 2025-02-01
Series:Cell Reports
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Online Access:http://www.sciencedirect.com/science/article/pii/S2211124725000312
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