In Vitro Antibacterial Spectrum of Sodium Selenite against Selected Human Pathogenic Bacterial Strains

The objective of this investigation was to predict the antibacterial properties of sodium selenite against selected human pathogens. A group of six human bacterial pathogens including Staphylococcus aureus, Streptococcus pyogenes, Bacillus subtilis, Escherichia coli, Pseudomonas aeruginosa, and Kleb...

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Main Authors: Mohammad Firoz Alam, Mohammed M. Safhi, Sivakumar Sivagurunathan Moni, Aamena Jabeen
Format: Article
Language:English
Published: Wiley 2016-01-01
Series:Scientifica
Online Access:http://dx.doi.org/10.1155/2016/9176273
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author Mohammad Firoz Alam
Mohammed M. Safhi
Sivakumar Sivagurunathan Moni
Aamena Jabeen
author_facet Mohammad Firoz Alam
Mohammed M. Safhi
Sivakumar Sivagurunathan Moni
Aamena Jabeen
author_sort Mohammad Firoz Alam
collection DOAJ
description The objective of this investigation was to predict the antibacterial properties of sodium selenite against selected human pathogens. A group of six human bacterial pathogens including Staphylococcus aureus, Streptococcus pyogenes, Bacillus subtilis, Escherichia coli, Pseudomonas aeruginosa, and Klebsiella planticola were utilized for screening. The spectrum of activity was qualified based on zone of inhibition. Our study demonstrated that sodium selenite exhibits a strong spectrum of activity against Bacillus subtilis, Staphylococcus aureus, Escherichia coli, and Klebsiella planticola. The spectrum of activity was compared with standard ciprofloxacin disc (5 μg/disc) and observed to have satisfactory effect.
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publishDate 2016-01-01
publisher Wiley
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series Scientifica
spelling doaj-art-8849b5aeca3a4b3087c8d882aa6385a42025-02-03T06:12:53ZengWileyScientifica2090-908X2016-01-01201610.1155/2016/91762739176273In Vitro Antibacterial Spectrum of Sodium Selenite against Selected Human Pathogenic Bacterial StrainsMohammad Firoz Alam0Mohammed M. Safhi1Sivakumar Sivagurunathan Moni2Aamena Jabeen3Department of Pharmacology & Toxicology, College of Pharmacy, Jazan University, P.O. Box 114, Jazan 45142, Saudi ArabiaDepartment of Pharmacology & Toxicology, College of Pharmacy, Jazan University, P.O. Box 114, Jazan 45142, Saudi ArabiaDivision of Pharmaceutical Biotechnology, Department of Pharmaceutics, College of Pharmacy, Jazan University, P.O. Box 114, Jazan 45142, Saudi ArabiaDivision of Pharmaceutical Biotechnology, Department of Pharmaceutics, College of Pharmacy, Jazan University, P.O. Box 114, Jazan 45142, Saudi ArabiaThe objective of this investigation was to predict the antibacterial properties of sodium selenite against selected human pathogens. A group of six human bacterial pathogens including Staphylococcus aureus, Streptococcus pyogenes, Bacillus subtilis, Escherichia coli, Pseudomonas aeruginosa, and Klebsiella planticola were utilized for screening. The spectrum of activity was qualified based on zone of inhibition. Our study demonstrated that sodium selenite exhibits a strong spectrum of activity against Bacillus subtilis, Staphylococcus aureus, Escherichia coli, and Klebsiella planticola. The spectrum of activity was compared with standard ciprofloxacin disc (5 μg/disc) and observed to have satisfactory effect.http://dx.doi.org/10.1155/2016/9176273
spellingShingle Mohammad Firoz Alam
Mohammed M. Safhi
Sivakumar Sivagurunathan Moni
Aamena Jabeen
In Vitro Antibacterial Spectrum of Sodium Selenite against Selected Human Pathogenic Bacterial Strains
Scientifica
title In Vitro Antibacterial Spectrum of Sodium Selenite against Selected Human Pathogenic Bacterial Strains
title_full In Vitro Antibacterial Spectrum of Sodium Selenite against Selected Human Pathogenic Bacterial Strains
title_fullStr In Vitro Antibacterial Spectrum of Sodium Selenite against Selected Human Pathogenic Bacterial Strains
title_full_unstemmed In Vitro Antibacterial Spectrum of Sodium Selenite against Selected Human Pathogenic Bacterial Strains
title_short In Vitro Antibacterial Spectrum of Sodium Selenite against Selected Human Pathogenic Bacterial Strains
title_sort in vitro antibacterial spectrum of sodium selenite against selected human pathogenic bacterial strains
url http://dx.doi.org/10.1155/2016/9176273
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AT sivakumarsivagurunathanmoni invitroantibacterialspectrumofsodiumseleniteagainstselectedhumanpathogenicbacterialstrains
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