Few regulatory metabolites coordinate expression of central metabolic genes in Escherichia coli

Abstract Transcription networks consist of hundreds of transcription factors with thousands of often overlapping target genes. While we can reliably measure gene expression changes, we still understand relatively little why expression changes the way it does. How does a coordinated response emerge i...

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Bibliographic Details
Main Authors: Karl Kochanowski, Luca Gerosa, Simon F Brunner, Dimitris Christodoulou, Yaroslav V Nikolaev, Uwe Sauer
Format: Article
Language:English
Published: Springer Nature 2017-01-01
Series:Molecular Systems Biology
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Online Access:https://doi.org/10.15252/msb.20167402
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