Chemical- and photo-activation of protein-protein thiol-ene coupling for protein profiling
Abstract The thiol-ene reaction between an alkene and a thiol can be exploited for selective labelling of cysteine residues in protein profiling applications. Here, we explore thiol-ene activation in systems from chemical models to complex cellular milieus, using UV, visible wavelength and redox ini...
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Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2025-01-01
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Series: | Communications Chemistry |
Online Access: | https://doi.org/10.1038/s42004-025-01412-6 |
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