Mild Cognitive Impairment and Depressive Symptoms in Elderly Patients with Diabetes: Prevalence, Risk Factors, and Comorbidity

The aim of the study was to estimate the prevalence of mild cognitive impairment (MCI), depressive syndrome cases, and its comorbidity, and to identify predictors of these conditions. Methods. 276 diabetics elders were screened for MCI and depressive symptoms. Detailed information of history of diab...

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Main Authors: Malgorzata Gorska-Ciebiada, Malgorzata Saryusz-Wolska, Maciej Ciebiada, Jerzy Loba
Format: Article
Language:English
Published: Wiley 2014-01-01
Series:Journal of Diabetes Research
Online Access:http://dx.doi.org/10.1155/2014/179648
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author Malgorzata Gorska-Ciebiada
Malgorzata Saryusz-Wolska
Maciej Ciebiada
Jerzy Loba
author_facet Malgorzata Gorska-Ciebiada
Malgorzata Saryusz-Wolska
Maciej Ciebiada
Jerzy Loba
author_sort Malgorzata Gorska-Ciebiada
collection DOAJ
description The aim of the study was to estimate the prevalence of mild cognitive impairment (MCI), depressive syndrome cases, and its comorbidity, and to identify predictors of these conditions. Methods. 276 diabetics elders were screened for MCI and depressive symptoms. Detailed information of history of diabetes, and data of BMI, HbA1c, and blood lipids were collected. Results. The prevalence of MCI was 31.5%, depressive syndrome was 29.7%, and MCI with coexisting depressive mood was 9.1%. The logistic regression analysis revealed that variables which increased the likelihood of having been diagnosed with MCI were: higher HbA1c level, previous CVD, hypertension, retinopathy, increased number of comorbidities, and less years of formal education. Significant predictors of having a depressive mood included female gender, single marital status, current and past smoking status, lack of physical activity, higher BMI and total cholesterol level, increased number of comorbidities, history of hypoglycemia, and insulin treatment. Factors associated with both MCI and depressive syndrome were female gender, single marital status, past smoking status, retinopathy, previous CVD or stroke, increased number of comorbidities, and insulin treatment. Conclusions. Depressive symptoms, MCI, and its comorbidity are common in elderly subjects with type 2 diabetes. Systematic screening could result in the identification of high-risk patients.
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series Journal of Diabetes Research
spelling doaj-art-8822615d7eee4b79b86d41cba810540b2025-02-03T01:24:21ZengWileyJournal of Diabetes Research2314-67452314-67532014-01-01201410.1155/2014/179648179648Mild Cognitive Impairment and Depressive Symptoms in Elderly Patients with Diabetes: Prevalence, Risk Factors, and ComorbidityMalgorzata Gorska-Ciebiada0Malgorzata Saryusz-Wolska1Maciej Ciebiada2Jerzy Loba3Department of Internal Medicine and Diabetology, Medical University of Lodz, 251 Pomorska Street, 92-213 Lodz, PolandDepartment of Internal Medicine and Diabetology, Medical University of Lodz, 251 Pomorska Street, 92-213 Lodz, PolandDepartment of General and Oncological Pneumology, Medical University of Lodz, 22 Kopcinskiego Street, 90-153 Lodz, PolandDepartment of Internal Medicine and Diabetology, Medical University of Lodz, 251 Pomorska Street, 92-213 Lodz, PolandThe aim of the study was to estimate the prevalence of mild cognitive impairment (MCI), depressive syndrome cases, and its comorbidity, and to identify predictors of these conditions. Methods. 276 diabetics elders were screened for MCI and depressive symptoms. Detailed information of history of diabetes, and data of BMI, HbA1c, and blood lipids were collected. Results. The prevalence of MCI was 31.5%, depressive syndrome was 29.7%, and MCI with coexisting depressive mood was 9.1%. The logistic regression analysis revealed that variables which increased the likelihood of having been diagnosed with MCI were: higher HbA1c level, previous CVD, hypertension, retinopathy, increased number of comorbidities, and less years of formal education. Significant predictors of having a depressive mood included female gender, single marital status, current and past smoking status, lack of physical activity, higher BMI and total cholesterol level, increased number of comorbidities, history of hypoglycemia, and insulin treatment. Factors associated with both MCI and depressive syndrome were female gender, single marital status, past smoking status, retinopathy, previous CVD or stroke, increased number of comorbidities, and insulin treatment. Conclusions. Depressive symptoms, MCI, and its comorbidity are common in elderly subjects with type 2 diabetes. Systematic screening could result in the identification of high-risk patients.http://dx.doi.org/10.1155/2014/179648
spellingShingle Malgorzata Gorska-Ciebiada
Malgorzata Saryusz-Wolska
Maciej Ciebiada
Jerzy Loba
Mild Cognitive Impairment and Depressive Symptoms in Elderly Patients with Diabetes: Prevalence, Risk Factors, and Comorbidity
Journal of Diabetes Research
title Mild Cognitive Impairment and Depressive Symptoms in Elderly Patients with Diabetes: Prevalence, Risk Factors, and Comorbidity
title_full Mild Cognitive Impairment and Depressive Symptoms in Elderly Patients with Diabetes: Prevalence, Risk Factors, and Comorbidity
title_fullStr Mild Cognitive Impairment and Depressive Symptoms in Elderly Patients with Diabetes: Prevalence, Risk Factors, and Comorbidity
title_full_unstemmed Mild Cognitive Impairment and Depressive Symptoms in Elderly Patients with Diabetes: Prevalence, Risk Factors, and Comorbidity
title_short Mild Cognitive Impairment and Depressive Symptoms in Elderly Patients with Diabetes: Prevalence, Risk Factors, and Comorbidity
title_sort mild cognitive impairment and depressive symptoms in elderly patients with diabetes prevalence risk factors and comorbidity
url http://dx.doi.org/10.1155/2014/179648
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