It takes two: Aberrant repair and low-grade inflammation characterize bronchiolitis obliterans syndrome after lung transplantation in serum proteomic analysis

It takes two: Aberrant repair and low-grade inflammation characterize bronchiolitis obliterans syndrome after lung transplantation in serum proteomic analysis

Background: The obstructive phenotype of chronic lung allograft dysfunction, bronchiolitis obliterans syndrome (BOS), is diagnosed after lung transplantation (LTx) when irreversible airway obstruction is already present. This study aimed to investigate biomarkers indicative of aberrant repair result...

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Main Authors: Eline A. van der Ploeg, Alen Faiz, Greta J. Teitsma, Alejandro Sánchez Brotons, Natalia Govorukhina, Jannie M.B. Sand, Diana J. Leeming, Barbro N. Melgert, Peter Horvatovich, Janette K. Burgess, C. Tji Gan
Format: Article
Language:English
Published: Elsevier 2025-08-01
Series:JHLT Open
Subjects:
bronchiolitis obliterans syndrome
chronic lung allograft dysfunction
lung transplantation
fibrosis
inflammation
Online Access:http://www.sciencedirect.com/science/article/pii/S2950133425000989
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http://www.sciencedirect.com/science/article/pii/S2950133425000989

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