ADGRB3-High and POSTN-High Fibroblasts Are Markers of Endotypic Traits in Chronic Rhinosinusitis

ADGRB3-High and POSTN-High Fibroblasts Are Markers of Endotypic Traits in Chronic Rhinosinusitis

Background: Chronic rhinosinusitis (CRS) is a disease characterized by persistent sinonasal mucosal inflammation. Fibroblasts play a crucial role in extracellular matrix production and inflammation. We investigated the heterogeneity of fibroblasts in patients with CRS. Methods: Fibroblasts were isol...

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Bibliographic Details
Main Authors: Hideyuki Takahashi, Toshiyuki Matsuyama, Reika Kawabata-Iwakawa, Yohei Morishita, Takayuki Kawamoto, Kazuaki Chikamatsu
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Immuno
Subjects:
chronic rhinosinusitis
nasal polyp
sinusitis
interleukin-13
interleukin-4
periostin
Online Access:https://www.mdpi.com/2673-5601/4/4/38
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