Targeted detection of sequence variants in cell-free DNA from cerebrospinal fluid in pediatric central nervous system tumors

Targeted detection of sequence variants in cell-free DNA from cerebrospinal fluid in pediatric central nervous system tumors

The emergence of liquid biopsy technologies holds great promise in the cancer setting, including in pediatric central nervous system (CNS) tumors. In contrast to broad lower-depth sequencing, commonly referred to as low pass whole genome sequencing (WGS), targeted platforms with a higher depth of co...

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Bibliographic Details
Main Authors: Katrina O’Halloran, Erin E. Crotty, Eirini Christodoulou, Sarah E. Leary, Alexandra Miller, Vera A. Paulson, Christina M. Lockwood, Ashley S. Margol, Jaclyn A. Biegel
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Oncology
Subjects:
pediatric neuro-oncology
cerebrospinal fluid
liquid biopsy
targeted sequencing
sequence variant
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2024.1513073/full
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https://www.frontiersin.org/articles/10.3389/fonc.2024.1513073/full

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