A multi-modal neuroimaging data release for Meige Syndrome and Facial Paralysis Research

Abstract The sharing of multimodal magnetic resonance imaging (MRI) data is of utmost importance in the field, as it enables a deeper understanding of facial nerve-related pathologies. However, there is a significant lack of multi-modal neuroimaging databases specifically focused on these conditions...

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Bibliographic Details
Main Authors: Peng Gao, Jixin Luan, Aocai Yang, Manxi Xu, Kuan Lv, Pianpian Hu, Hongwei Yu, Zeshan Yao, Guolin Ma
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Scientific Data
Online Access:https://doi.org/10.1038/s41597-025-04383-4
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Summary:Abstract The sharing of multimodal magnetic resonance imaging (MRI) data is of utmost importance in the field, as it enables a deeper understanding of facial nerve-related pathologies. However, there is a significant lack of multi-modal neuroimaging databases specifically focused on these conditions, which hampers our comprehensive knowledge of the neural foundations of facial paralysis. To address this critical gap and propel advancements in this area, we have released the Multimodal Neuroimaging Dataset of Meige Syndrome, Facial Paralysis, and Healthy Controls (MND-MFHC). This dataset includes detailed clinical assessments of 53 individuals with facial paralysis (FP), 31 patients with Meige syndrome (MS), and 102 healthy controls (HC). To promote open access, the BIDS-formatted data and associated quality control reports can be accessed through the Science Data Bank (SciDB). By sharing this comprehensive dataset, our aim is to facilitate further research and exploration into the intricate neural mechanisms underlying facial nerve-related pathologies.
ISSN:2052-4463