Exercise-induced PV network plasticity in the prelimbic cortex regulates the expression of fear memory in male mice

Abstract Many psychiatric disorders, such as anxiety disorders, are characterized by abnormal processing of fear-related information. Parvalbumin (PV) neurons in the prelimbic cortex (PL) are critically involved in fear expression. However, the role of plasticity of the local PV neuron network in th...

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Bibliographic Details
Main Authors: Neng-Yuan Hu, Xin Heng, Hao Li, Lang Huang, Yuan-Yue Dou, Yi-Hua Chen
Format: Article
Language:English
Published: Nature Publishing Group 2025-07-01
Series:Translational Psychiatry
Online Access:https://doi.org/10.1038/s41398-025-03472-7
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