The Proteomic Analysis of Platelet Extracellular Vesicles in Diabetic Patients by nanoLC-MALDI-MS/MS and nanoLC-TIMS-MS/MS

The Proteomic Analysis of Platelet Extracellular Vesicles in Diabetic Patients by nanoLC-MALDI-MS/MS and nanoLC-TIMS-MS/MS

Platelet extracellular vesicles (PEVs) are emerging as key biomarkers in diabetes mellitus (DM), reflecting altered platelet function and coagulation pathways. This study compares two proteomic techniques—nanoLC-MALDI-MS/MS and nanoLC-TIMS-MS/MS—for analyzing PEVs in diabetic patients, to assess the...

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Bibliographic Details
Main Authors: Joanna Kasprzyk-Pochopień, Agnieszka Kamińska, Przemysław Mielczarek, Radosław Porada, Ewa Stępień, Wojciech Piekoszewski
Format: Article
Language:English
Published: MDPI AG 2025-03-01
Series:Molecules
Subjects:
proteomic analysis
platelet extracellular vesicles (PEVs)
diabetes mellitus
nanoLC-MALDI-MS/MS
nanoLC-TIMS-MS/MS
biomarker discovery
Online Access:https://www.mdpi.com/1420-3049/30/6/1384
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