Association between serum α-klotho levels and the incidence of diabetic kidney disease and mortality in type 2 diabetes: evidence from a Chinese cohort and the NHANES database

Association between serum α-klotho levels and the incidence of diabetic kidney disease and mortality in type 2 diabetes: evidence from a Chinese cohort and the NHANES database

Abstract Background The α-klotho is crucial in diabetes and its related complications. This study seeks to explore the link between α-klotho levels and the risk of diabetic kidney disease (DKD) as well as all-cause and cardiovascular mortality among individuals with type 2 diabetes mellitus (T2DM)....

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Bibliographic Details
Main Authors: Yi Kang, Qian Jin, Mengqi Zhou, Huijuan Zheng, Danwen Li, Jingwei Zhou, Jie Lv, Yaoxian Wang
Format: Article
Language:English
Published: BMC 2025-05-01
Series:Diabetology & Metabolic Syndrome
Subjects:
α-klotho
Type 2 diabetes
Diabetic kidney disease
All-cause mortality
Cardiovascular mortality
Online Access:https://doi.org/10.1186/s13098-025-01711-x
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