Ginsenoside 20(S)-Rg3 upregulates SQLE to reprogram cholesterol metabolism of ovarian cancer cells

Summary: Ginsenoside 20(S)-Rg3 exhibits the anti-ovarian cancer activity by modulating aerobic glycolysis, but its role in reprogramming sterol metabolism remains unclear. This research utilized transcriptomic and lipidomic to identify the key metabolic pathways and targets influenced by 20(S)-Rg3....

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Bibliographic Details
Main Authors: Fang He, Yuanyuan Zhou, Jing Fu, ShiXue Chang, Xi Cui, Zhaozu Feng, Le Zhao, Xu Li
Format: Article
Language:English
Published: Elsevier 2025-08-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004225011149
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