Protocols for the application of human embryonic stem cell-derived neurons for aging modeling and gene manipulation

Protocols for the application of human embryonic stem cell-derived neurons for aging modeling and gene manipulation

Summary: In vitro models of neuronal aging and gene manipulation in human neurons (hNeurons) are valuable tools for investigating human brain aging and diseases. Here, we present a protocol for applying human embryonic stem cell (hESC)-derived neurons to model aging and the further application of sm...

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Bibliographic Details
Main Authors:	Hui Zhang, Shuhui Sun, Juan Carlos Izpisua Belmonte, Guang-Hui Liu, Si Wang, Weiqi Zhang, Jing Qu
Format:	Article
Language:	English
Published:	Elsevier 2025-03-01
Series:	STAR Protocols
Subjects:	Cell Biology Developmental biology Molecular Biology Neuroscience Stem Cells Cell Differentiation
Online Access:	http://www.sciencedirect.com/science/article/pii/S2666166725000395
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