Titanium implant can promote M2 polarization with macrophages activation which contribute to osteogenesis and angiogenesis via inactivates JAKS signaling pathway

Abstract Implants can regulate the phenotypic transformation of macrophages from pro-inflammatory M1-type to anti-inflammatory M2-type, and macrophage polarization plays an important role in the process of osteogenesis and angiogenesis. This study aims to explore the potential mechanism of the regul...

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Bibliographic Details
Main Authors: Xiao Luo, Lin Xiao
Format: Article
Language:English
Published: BMC 2025-07-01
Series:BMC Immunology
Subjects:
Online Access:https://doi.org/10.1186/s12865-025-00729-0
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