Fedratinib for the treatment of myelofibrosis: a critical appraisal of clinical trial and “real-world” data

Abstract Fedratinib is a predominantly JAK2 inhibitor that has shown efficacy in untreated and ruxolitinib-exposed patients with myelofibrosis (MF). Based on randomized clinical trial data, it is approved for use in patients with International Prognostic Scoring System (IPSS) or Dynamic Internationa...

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Bibliographic Details
Main Authors: Adrian Duek, Ilona Leviatan, Osnat Jarchowsky Dolberg, Martin H. Ellis
Format: Article
Language:English
Published: Nature Publishing Group 2025-01-01
Series:Blood Cancer Journal
Online Access:https://doi.org/10.1038/s41408-025-01211-1
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