Quasi-Complete Response of Classic Kaposi’s Sarcoma Treated with Weekly Paclitaxel
Classic Kaposi’s sarcoma (CKS) is a subtype that traditionally occurs in elderly HIV-negative males of Mediterranean origin. Patients with CKS characteristically present with skin lesions in the distal extremities. Involvement of the viscera is uncommon but may occur in the late stages of the diseas...
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| Format: | Article |
| Language: | English |
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Wiley
2013-01-01
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| Series: | Case Reports in Oncological Medicine |
| Online Access: | http://dx.doi.org/10.1155/2013/196878 |
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| author | Zineb Benbrahim Samia Arifi Hafida Benhammane Kaoutar Inani Salim Gallouj Meriem Meziane Fatima Zahra Mernissi Nawfel Mellas Omar El Mesbahi |
| author_facet | Zineb Benbrahim Samia Arifi Hafida Benhammane Kaoutar Inani Salim Gallouj Meriem Meziane Fatima Zahra Mernissi Nawfel Mellas Omar El Mesbahi |
| author_sort | Zineb Benbrahim |
| collection | DOAJ |
| description | Classic Kaposi’s sarcoma (CKS) is a subtype that traditionally occurs in elderly HIV-negative males of Mediterranean origin. Patients with CKS characteristically present with skin lesions in the distal extremities. Involvement of the viscera is uncommon but may occur in the late stages of the disease. Patients with extensive KS can be treated with systemic chemotherapy. A number of drugs approved for treatment of AIDS-associated KS, especially Paclitaxel, have activity against CKS after failure of prior therapy. We report a patient treated with weekly Paclitaxel, as initial chemotherapy, for CKS presenting with multiple visceral involvement and having a contraindication for Bleomycin. The patient had quasi-complete response after three months of chemotherapy suggesting that weekly Paclitaxel might be effective as a first-line therapy for classical type KS with visceral involvement. |
| format | Article |
| id | doaj-art-8655e006ab2c4a20acef3a1ac4a6c3d3 |
| institution | Kabale University |
| issn | 2090-6706 2090-6714 |
| language | English |
| publishDate | 2013-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Oncological Medicine |
| spelling | doaj-art-8655e006ab2c4a20acef3a1ac4a6c3d32025-02-03T06:12:44ZengWileyCase Reports in Oncological Medicine2090-67062090-67142013-01-01201310.1155/2013/196878196878Quasi-Complete Response of Classic Kaposi’s Sarcoma Treated with Weekly PaclitaxelZineb Benbrahim0Samia Arifi1Hafida Benhammane2Kaoutar Inani3Salim Gallouj4Meriem Meziane5Fatima Zahra Mernissi6Nawfel Mellas7Omar El Mesbahi8Medical Oncology, Hassan II University Hospital, P.O. Box 8743, Fès, MoroccoMedical Oncology, Hassan II University Hospital, P.O. Box 8743, Fès, MoroccoMedical Oncology, Hassan II University Hospital, P.O. Box 8743, Fès, MoroccoService of Dermatology, Hassan II University Hospital, Fès, MoroccoService of Dermatology, Hassan II University Hospital, Fès, MoroccoService of Dermatology, Hassan II University Hospital, Fès, MoroccoService of Dermatology, Hassan II University Hospital, Fès, MoroccoMedical Oncology, Hassan II University Hospital, P.O. Box 8743, Fès, MoroccoMedical Oncology, Hassan II University Hospital, P.O. Box 8743, Fès, MoroccoClassic Kaposi’s sarcoma (CKS) is a subtype that traditionally occurs in elderly HIV-negative males of Mediterranean origin. Patients with CKS characteristically present with skin lesions in the distal extremities. Involvement of the viscera is uncommon but may occur in the late stages of the disease. Patients with extensive KS can be treated with systemic chemotherapy. A number of drugs approved for treatment of AIDS-associated KS, especially Paclitaxel, have activity against CKS after failure of prior therapy. We report a patient treated with weekly Paclitaxel, as initial chemotherapy, for CKS presenting with multiple visceral involvement and having a contraindication for Bleomycin. The patient had quasi-complete response after three months of chemotherapy suggesting that weekly Paclitaxel might be effective as a first-line therapy for classical type KS with visceral involvement.http://dx.doi.org/10.1155/2013/196878 |
| spellingShingle | Zineb Benbrahim Samia Arifi Hafida Benhammane Kaoutar Inani Salim Gallouj Meriem Meziane Fatima Zahra Mernissi Nawfel Mellas Omar El Mesbahi Quasi-Complete Response of Classic Kaposi’s Sarcoma Treated with Weekly Paclitaxel Case Reports in Oncological Medicine |
| title | Quasi-Complete Response of Classic Kaposi’s Sarcoma Treated with Weekly Paclitaxel |
| title_full | Quasi-Complete Response of Classic Kaposi’s Sarcoma Treated with Weekly Paclitaxel |
| title_fullStr | Quasi-Complete Response of Classic Kaposi’s Sarcoma Treated with Weekly Paclitaxel |
| title_full_unstemmed | Quasi-Complete Response of Classic Kaposi’s Sarcoma Treated with Weekly Paclitaxel |
| title_short | Quasi-Complete Response of Classic Kaposi’s Sarcoma Treated with Weekly Paclitaxel |
| title_sort | quasi complete response of classic kaposi s sarcoma treated with weekly paclitaxel |
| url | http://dx.doi.org/10.1155/2013/196878 |
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