Vaccine hesitancy or hesitancies? A latent class analysis of pediatric patients' parents

Abstract Vaccine hesitancy is an attitude of indecision toward vaccination that is related to but not determinative of vaccination behaviors. Although theories of vaccine hesitancy emphasize it is often vaccine‐specific, we do not know the extent to which this is true across sociodemographic groups....

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Main Authors: Don E. Willis, Marie‐Rachelle Narcisse, Laura James, James P. Selig, Mohammed Ason, Aaron J. Scott, Lawrence E. Cornett, Pearl A. McElfish
Format: Article
Language:English
Published: Wiley 2025-01-01
Series:Clinical and Translational Science
Online Access:https://doi.org/10.1111/cts.70042
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author Don E. Willis
Marie‐Rachelle Narcisse
Laura James
James P. Selig
Mohammed Ason
Aaron J. Scott
Lawrence E. Cornett
Pearl A. McElfish
author_facet Don E. Willis
Marie‐Rachelle Narcisse
Laura James
James P. Selig
Mohammed Ason
Aaron J. Scott
Lawrence E. Cornett
Pearl A. McElfish
author_sort Don E. Willis
collection DOAJ
description Abstract Vaccine hesitancy is an attitude of indecision toward vaccination that is related to but not determinative of vaccination behaviors. Although theories of vaccine hesitancy emphasize it is often vaccine‐specific, we do not know the extent to which this is true across sociodemographic groups. In this study, we asked: What latent classes of vaccine hesitancy might exist when examining parents' attitudes toward vaccines in general and COVID‐19 and human papillomavirus (HPV) vaccination specifically? Which sociodemographic, health access, and health‐related variables are predictive of membership in those classes? To answer those questions, we analyze online survey data from parents of pediatric patients recruited through eight clinics within the University of Arkansas for Medical Sciences Rural Research Network. Data were collected between September 16, 2022 and December 6, 2022. Latent class analysis revealed three underlying classes of vaccine hesitancy, or hesitancies: The “Selectively Hesitant,” the “COVID‐Centric Hesitant,” and the “Pervasively Hesitant.” Significant predictors of class membership were age, education, health insurance status, and usual source of care. Vaccine hesitancy may be specific to certain vaccines for some parents and more generalized for others. The distinct classes of vaccine hesitancy revealed in this study suggest the need for distinct approaches to addressing vaccine hesitancy depending on the population.
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spelling doaj-art-8655d1e3300241b6b8b1e5b7a74a6baf2025-01-24T08:17:46ZengWileyClinical and Translational Science1752-80541752-80622025-01-01181n/an/a10.1111/cts.70042Vaccine hesitancy or hesitancies? A latent class analysis of pediatric patients' parentsDon E. Willis0Marie‐Rachelle Narcisse1Laura James2James P. Selig3Mohammed Ason4Aaron J. Scott5Lawrence E. Cornett6Pearl A. McElfish7College of Medicine University of Arkansas for Medical Sciences Northwest Springdale Arkansas USADepartment of Psychiatry and Human Behavior Brown University Providence Rhode Island USACollege of Medicine University of Arkansas for Medical Sciences Little Rock Arkansas USAFay W. Boozman College of Public Health University of Arkansas for Medical Sciences Northwest Springdale Arkansas USAInstitute for Community Health Innovation University of Arkansas for Medical Sciences Northwest Springdale Arkansas USAInstitute for Community Health Innovation University of Arkansas for Medical Sciences Northwest Springdale Arkansas USACollege of Medicine University of Arkansas for Medical Sciences Little Rock Arkansas USACollege of Medicine University of Arkansas for Medical Sciences Northwest Springdale Arkansas USAAbstract Vaccine hesitancy is an attitude of indecision toward vaccination that is related to but not determinative of vaccination behaviors. Although theories of vaccine hesitancy emphasize it is often vaccine‐specific, we do not know the extent to which this is true across sociodemographic groups. In this study, we asked: What latent classes of vaccine hesitancy might exist when examining parents' attitudes toward vaccines in general and COVID‐19 and human papillomavirus (HPV) vaccination specifically? Which sociodemographic, health access, and health‐related variables are predictive of membership in those classes? To answer those questions, we analyze online survey data from parents of pediatric patients recruited through eight clinics within the University of Arkansas for Medical Sciences Rural Research Network. Data were collected between September 16, 2022 and December 6, 2022. Latent class analysis revealed three underlying classes of vaccine hesitancy, or hesitancies: The “Selectively Hesitant,” the “COVID‐Centric Hesitant,” and the “Pervasively Hesitant.” Significant predictors of class membership were age, education, health insurance status, and usual source of care. Vaccine hesitancy may be specific to certain vaccines for some parents and more generalized for others. The distinct classes of vaccine hesitancy revealed in this study suggest the need for distinct approaches to addressing vaccine hesitancy depending on the population.https://doi.org/10.1111/cts.70042
spellingShingle Don E. Willis
Marie‐Rachelle Narcisse
Laura James
James P. Selig
Mohammed Ason
Aaron J. Scott
Lawrence E. Cornett
Pearl A. McElfish
Vaccine hesitancy or hesitancies? A latent class analysis of pediatric patients' parents
Clinical and Translational Science
title Vaccine hesitancy or hesitancies? A latent class analysis of pediatric patients' parents
title_full Vaccine hesitancy or hesitancies? A latent class analysis of pediatric patients' parents
title_fullStr Vaccine hesitancy or hesitancies? A latent class analysis of pediatric patients' parents
title_full_unstemmed Vaccine hesitancy or hesitancies? A latent class analysis of pediatric patients' parents
title_short Vaccine hesitancy or hesitancies? A latent class analysis of pediatric patients' parents
title_sort vaccine hesitancy or hesitancies a latent class analysis of pediatric patients parents
url https://doi.org/10.1111/cts.70042
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