Dexrazoxane preferentially mitigates doxorubicin cardiotoxicity in female children with sarcoma

Dexrazoxane preferentially mitigates doxorubicin cardiotoxicity in female children with sarcoma

Objective We sought to determine how sex and dexrazoxane therapy influence cardiac remodelling in children with sarcoma receiving high-dose doxorubicin.Methods In a retrospective cohort of 85 children with sarcoma receiving high-dose doxorubicin, echocardiography measures prior to, early after (with...

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Main Authors: Hari K Narayan, Mary E Putt, Nikitha Kosaraju, Alejandro Paz, Shivani Bhatt, Theodore Plappert, Laura Mercer-Rosa, Saro H Armenian, Ami V Desai, Richard B Womer, Bonnie Ky
Format: Article
Language:English
Published: BMJ Publishing Group 2019-05-01
Series:Open Heart
Online Access:https://openheart.bmj.com/content/6/1/e001025.full
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https://openheart.bmj.com/content/6/1/e001025.full

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