Rituximab treatment in hepatitis C infection: an in vitro model to study the impact of B cell depletion on virus infectivity.

Hepatitis C virus (HCV) infected patients with vasculitis are often treated with the B-cell-depleting anti-CD20 antibody rituximab. Treatment reduces the cryoglobulins that cause vasculitis, yet it also leads to a transient increase in liver enzymes and HCV genomic RNA in the periphery. The mechanis...

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Bibliographic Details
Main Authors: Zania Stamataki, Samantha Tilakaratne, David H Adams, Jane A McKeating
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0025789&type=printable
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