Timcodar (VX-853) Is a Non-FKBP12 Binding Macrolide Derivative That Inhibits PPARγ and Suppresses Adipogenesis

Nutrient overload and genetic factors have led to a worldwide epidemic of obesity that is the underlying cause of diabetes, atherosclerosis, and cardiovascular disease. In this study, we used macrolide drugs such as FK506, rapamycin, and macrolide derived, timcodar (VX-853), to determine their effec...

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Bibliographic Details
Main Authors: Terry D. Hinds, Kezia John, Lucien McBeth, Christopher J. Trabbic, Edwin R. Sanchez
Format: Article
Language:English
Published: Wiley 2016-01-01
Series:PPAR Research
Online Access:http://dx.doi.org/10.1155/2016/6218637
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