p53-Dependent Senescence in Mesenchymal Stem Cells under Chronic Normoxia Is Potentiated by Low-Dose γ-Irradiation

p53-Dependent Senescence in Mesenchymal Stem Cells under Chronic Normoxia Is Potentiated by Low-Dose γ-Irradiation

Mesenchymal stem cells (MSCs) are a source of adult multipotent cells important in tissue regeneration. Murine MSCs are known to proliferate poorly in vitro under normoxia. The aim of this study is to analyze the interaction of nonphysiological high oxygen and low-dose γ-irradiation onto growth, sen...

Full description

Saved in:
Bibliographic Details
Main Authors: Ines Höfig, Yashodhara Ingawale, Michael J. Atkinson, Heidi Hertlein, Peter J. Nelson, Michael Rosemann
Format: Article
Language:English
Published: Wiley 2016-01-01
Series:Stem Cells International
Online Access:http://dx.doi.org/10.1155/2016/6429853
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items

Similar Items