Virulence-associated variants in Cryptococcus neoformans sequence type 93 are less likely to be associated with population structure compared to independent rare mutations

Virulence-associated variants in Cryptococcus neoformans sequence type 93 are less likely to be associated with population structure compared to independent rare mutations

ABSTRACT Cryptococcus neoformans is a pathogenic yeast that is the causative agent of cryptococcal meningitis. While it is well known that the genotype of C. neoformans impacts patient outcomes, the reason for this association has not been well elucidated. In this study, we examined the relationship...

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Main Authors: Katrina M. Jackson, Kisakye Diana Kabbale, Marissa Macchietto, David Meya, Peter Tiffin, Kirsten Nielsen
Format: Article
Language:English
Published: American Society for Microbiology 2025-01-01
Series:Microbiology Spectrum
Subjects:
Cryptococcus neoformans
linkage disequilirium
population genetics
molecular genetics
virulence determinants
mycology
Online Access:https://journals.asm.org/doi/10.1128/spectrum.01709-24
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https://journals.asm.org/doi/10.1128/spectrum.01709-24

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